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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ARG63766.100 | 100 µg | - | - |
6 - 14 business days* |
784.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions... more
Product information "Anti-Serotonin receptor 2C / HTR2C, Internal"
Protein function: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including ergot alkaloid derivatives, 1- 2,5,-dimethoxy-4-iodophenyl-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and down-stream signaling cascades and promotes the release of Ca(2+) ions from intracellular stores. Regulates neuronal activity via the activation of short transient receptor potential calcium channels in the brain, and thereby modulates the activation of pro-opiomelacortin neurons and the release of CRH that then regulates the release of corticosterone. Plays a role in the regulation of appetite and eating behavior, responses to anxiogenic stimuli and stress. Plays a role in insulin sensitivity and glucose homeostasis. [The UniProt Consortium]
Keywords: | Anti-HTR2C, Anti-HTR1C, Anti-5-HT1C, Anti-5-HT2C, Anti-5-HT-2C, Anti-5-HTR2C, Anti-5-HT-1C, Anti-Serotonin receptor 2C, Anti-5-hydroxytryptamine receptor 2C, Anti-5-hydroxytryptamine receptor 1C |
Supplier: | Arigo Biolaboratories |
Supplier-Nr: | ARG63766 |
Properties
Application: | ELISA, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Goat |
Species reactivity: | human (Expected: mouse, rat, canine, bovine) |
Immunogen: | C-QVENLELPVN |
Format: | Ammonium Sulfate Precipitated |
Database Information
KEGG ID : | K04157 | Matching products |
UniProt ID : | P28335 | Matching products |
Gene ID | GeneID 3358 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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