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![Anti-SARS-CoV-2 N Protein, mAb (rec.) (AB83-C12)](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
AG-27B-6306-C050 | 50 µg | - |
3 - 9 business days* |
317.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Coronaviruses (CoVs) are enveloped non-segmented positive-sense single-stranded RNA viruses and... more
Product information "Anti-SARS-CoV-2 N Protein, mAb (rec.) (AB83-C12)"
Coronaviruses (CoVs) are enveloped non-segmented positive-sense single-stranded RNA viruses and can infect respiratory, gastrointestinal, hepatic and central nervous system of human and many other wild animals. Recently, a new severe acute respiratory syndrome beta-coronavirus called SARS-CoV-2 (or 2019-nCoV) has emerged, which causes an epidemic of acute respiratory syndrome (called coronavirus human disease 2019 or COVID-19). SARS-CoV-2 shares 79.5% sequence identity with SARS-CoV and is 96.2% identical at the genome level to the bat coronavirus BatCoV RaTG133, suggesting it had originated in bats. SARS-CoV-2 contains 4 structural proteins, including Envelope (E), Membrane (M), Nucleocapsid (N) and Spike (S), which is a transmembrane protein, composed of two subunits S1 and S2. The S1 subunit contains a receptor binding domain (RBD), which binds to the cell surface receptor Angiotensin-Converting Enzyme 2 (ACE2) present at the surface of epithelial cells, causing mainly infection of human respiratory cells. The N protein contains two domains, both of them bind the virus RNA genome via different mechanisms. The N protein packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Protein function: Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication (PubMed:17210170). May modulate transforming growth factor-beta signaling by binding host SMAD3 (PubMed:18055455). [The UniProt Consortium]
Keywords: | Anti-9a, Anti-NC, Anti-Protein N, Anti-Nucleoprotein, Anti-Nucleocapsid protein |
Supplier: | AdipoGen Life Sciences |
Supplier-Nr: | AG-27B-6306 |
Properties
Application: | ELISA, ICC, WB |
Antibody Type: | Monoclonal |
Clone: | AB83-C12 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | SARS-CoV-2 |
Immunogen: | Recombinant SARS-CoV-2 Nucleocapsid protein (aa 1-419) containing a C-terminal His-tag. |
Format: | Purified |
Database Information
UniProt ID : | P59595 | Matching products |
Gene ID | GeneID 1489678 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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