Anti-RXR beta / RXRB, clone PCRP-RXRB-2B6

1 mg/ml in 1X PBS, BSA free, sodium azide free. Two families of retinoid receptors, RARs and RXRs, have been identified. Retinoic acid receptors (RARs) include RAR, are activated by 9-cis-RA, a stereo- and photo-isomer of all trans-RA that is expressed in vivo in both liver and kidney and may represent a widely used hormone. As is true for the RAR subfamily, the RXR receptors are closely related to each other both in their DNA-binding and ligand-binding domains and are encoded by separate genes at distinct chromosomal loci. Protein function: Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE). [The UniProt Consortium]