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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A301-266A-T | 10 µl (2 µg) | - |
2 - 8 business days* |
164.00€
|
|||
A301-266A | 100 µl | - |
2 - 8 business days* |
588.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Receptor for SLIT1 and SLIT2 that mediates cellular responses to molecular... more
Product information "Anti-ROBO1"
Protein function: Receptor for SLIT1 and SLIT2 that mediates cellular responses to molecular guidance cues in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development (PubMed:10102268, PubMed:24560577). Interaction with the intracellular domain of FLRT3 mediates axon attraction towards cells expressing NTN1 (PubMed:24560577). In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex. Plays a role in the regulation of cell migration via its interaction with MYO9B, inhibits MYO9B-mediated stimulation of RHOA GTPase activity, and thereby leads to increased levels of active, GTP- bound RHOA (PubMed:26529257). May be required for lung development. [The UniProt Consortium]
Keywords: | Anti-DUTT1, Anti-ROBO1, Anti-H-Robo-1, Anti-Roundabout homolog 1, Anti-Deleted in U twenty twenty |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A301-266A |
Properties
Application: | WB, IP |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human (Expected: bovine, dog, rabbit, pig, panda, rhesus monkey, gorilla, chimpanzee, white-tufted-ear marmoset, african elephant, small-eared galago, thirteen-lined ground squirrel, little brown bat, northern white-cheeked gibbon) |
Immunogen: | synthetic peptide. The epitope recognized by A301-266A-T maps to a region between residue 1601 and 1651 of human roundabout, axon guidance receptor, homolog 1 using the numbering given in entry NP_002932.1 (GeneID 6091). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K06753 | Matching products |
UniProt ID : | Q9Y6N7 | Matching products |
Gene ID : | GeneID 6091 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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