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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The protein encoded by this gene contains a RING finger, which is a motif known to be involved in... more
Product information "Anti-RNF5"
The protein encoded by this gene contains a RING finger, which is a motif known to be involved in protein-protein interactions. This protein is a membrane-bound ubiquitin ligase. It can regulate cell motility by targeting paxillin ubiquitination and altering the distribution and localization of paxillin in cytoplasm and cell focal adhesions. Protein function: Has E2-dependent E3 ubiquitin-protein ligase activity. May function together with E2 ubiquitin-conjugating enzymes UBE2D1/UBCH5A and UBE2D2/UBC4. Mediates ubiquitination of PXN/paxillin and Salmonella type III secreted protein sopA. May be involved in regulation of cell motility and localization of PXN/paxillin. Mediates the 'Lys-63'-linked polyubiquitination of JKAMP thereby regulating JKAMP function by decreasing its association with components of the proteasome and ERAD, the ubiquitination appears to involve E2 ubiquitin-conjugating enzyme UBE2N. Mediates the 'Lys-48'-linked polyubiquitination of TMEM173 at 'Lys-150' leading to its proteasomal degradation, the ubiquitination occurs in mitochondria after viral transfection and regulates antiviral responses. [The UniProt Consortium]
Keywords: | Anti-G16, Anti-RNF5, Anti-HsRma1, EC=2.3.2.27, Anti-Protein G16, Anti-Ram1 homolog, Anti-RING finger protein 5, Anti-E3 ubiquitin-protein ligase RNF5, Anti-RING-type E3 ubiquitin transferase RNF5, RNF5 Polyclonal Antibody |
Supplier: | Elabscience |
Supplier-Nr: | E-AB-62197 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | Recombinant protein of human RNF5 |
Database Information
KEGG ID : | K10666 | Matching products |
UniProt ID : | Q99942 | Matching products |
Gene ID : | GeneID 6048 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | 4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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