Anti-RIP3

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A304-378A-T	10 µl (10 µg)		-		2 - 8 business days*		178.00€
A304-378A	100 µl (100 µg)		-		2 - 8 business days*		630.00€

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Protein function: Essential for necroptosis, a programmed cell death process in response to... more

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Product information "Anti-RIP3"

Protein function: Essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes may eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production. [The UniProt Consortium]

Keywords:	Anti-RIP3, Anti-RIPK3, Anti-RIP-3, EC=2.7.11.1, Anti-RIP-like protein kinase 3, Anti-Receptor-interacting protein 3, Anti-Receptor-interacting serine/threonine-protein kinase 3
Supplier:	Bethyl Laboratories
Supplier-Nr:	A304-378A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: orangutan, gorilla, chimpanzee)
Immunogen:	synthetic peptide. The epitope recognized by A304-378A-T maps to a region between residue 400 to 450 of human Receptor Interacting Protein 3 using the numbering given in entry NP_006862.2 (GeneID 11035).
Format:	Antigen Affinity Purified