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![Anti-RGMA, clone CL11342](https://www.biomol.com/media/image/d7/71/bf/ATA-AMAb91702-25_600x600.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ATA-AMAb91702.25 | 25 µl | - |
7 - 10 business days* |
335.00€
|
|||
ATA-AMAb91702.100 | 100 µl | - |
7 - 10 business days* |
446.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Member of the repulsive guidance molecule (RGM) family that performs several... more
Product information "Anti-RGMA, clone CL11342"
Protein function: Member of the repulsive guidance molecule (RGM) family that performs several functions in the developing and adult nervous system. Regulates cephalic neural tube closure, inhibits neurite outgrowth and cortical neuron branching, and the formation of mature synapses. Binding to its receptor NEO1/neogenin induces activation of RHOA- ROCK1/Rho-kinase signaling pathway through UNC5B-ARHGEF12/LARG- PTK2/FAK1 cascade, leading to collapse of the neuronal growth cone and neurite outgrowth inhibition. Furthermore, RGMA binding to NEO1/neogenin leads to HRAS inactivation by influencing HRAS-PTK2/FAK1- AKT1 pathway. It also functions as a bone morphogenetic protein (BMP) coreceptor that may signal through SMAD1, SMAD5, and SMAD8. [The UniProt Consortium] Validated by standard strategies. Buffer: The antibodies are delivered in 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Keywords: | Anti-RGM, Anti-RGMA, Anti-RGM domain family member A, Anti-Repulsive guidance molecule A |
Supplier: | Atlas Antibodies |
Supplier-Nr: | AMAb91702 |
Properties
Application: | WB |
Antibody Type: | Monoclonal |
Clone: | CL11342 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Synthetic Peptide: DGSKNGGDKH GANSLKITEK |
Database Information
KEGG ID : | K23096 | Matching products |
UniProt ID : | Q96B86 | Matching products |
Gene ID | GeneID 56963 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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