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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ATA-HPA047435.25 | 25 µl | - |
7 - 10 business days* |
239.00€
|
|||
| ATA-HPA047435.100 | 100 µl | - |
7 - 10 business days* |
477.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Essential subunit of the gamma-secretase complex, an endoprotease complex that... more
Product information "Anti-PSENEN"
Protein function: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid- beta precursor protein) (PubMed:12522139, PubMed:12763021, PubMed:12740439, PubMed:12679784, PubMed:24941111, PubMed:30598546, PubMed:30630874). The gamma-secretase complex plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels (Probable). PSENEN modulates both endoproteolysis of presenilin and gamma-secretase activity (PubMed:12522139, PubMed:12763021, PubMed:12740439, PubMed:12679784, PubMed:24941111). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 95% and to rat: 86%
| Keywords: | Anti-PEN2, Anti-PSENEN, Anti-MDS033, Anti-Presenilin enhancer protein 2, Anti-Gamma-secretase subunit PEN-2 |
| Supplier: | Atlas Antibodies |
| Supplier-Nr: | HPA047435 |
Properties
| Application: | IHC |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human |
| Immunogen: | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: FREAFLVPAY TEQSQIKGYV W (ATA-APrEST82877) |
Database Information
| KEGG ID : | K06170 | Matching products |
| UniProt ID : | Q9NZ42 | Matching products |
| Gene ID : | GeneID 55851 | Matching products |
| Protein Atlas Nr. : | ENSG00000205155 |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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