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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A304-188A-T | 10 µl (10 µg) | - |
2 - 8 business days* |
164.00€
|
|||
A304-188A | 100 µl (100 µg) | - |
2 - 8 business days* |
588.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Subunit of mTORC2, which regulates cell growth and survival in response to... more
Product information "Anti-Protor-1"
Protein function: Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient- insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 on 'Thr-308' by PDK1 which is a prerequisite for full activation. mTORC2 regulates the phosphorylation of SGK1 at 'Ser-422'. mTORC2 also modulates the phosphorylation of PRKCA on 'Ser-657'. PRR5 plays an important role in regulation of PDGFRB expression and in modulation of platelet-derived growth factor signaling. May act as a tumor suppressor in breast cancer. [The UniProt Consortium]
Keywords: | Anti-PRR5, Anti-PP610, Anti-PROTOR1, Anti-Protor-1, Anti-Proline-rich protein 5, Anti-Protein observed with Rictor-1 |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A304-188A |
Properties
Application: | WB, IP |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human (Expected: chimpanzee, northern white-cheeked gibbon) |
Immunogen: | synthetic peptide. The epitope recognized by A304-188A-T maps to a region between residue 338 to 388 of human Protein Observed with Rictor-1 using the numbering given in entry NP_851850.1 (GeneID 55615). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K20411 | Matching products |
UniProt ID : | P85299 | Matching products |
Gene ID : | GeneID 55615 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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