Anti-Progranulin (mouse)

Anti-Progranulin (mouse)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
AG-25A-0093-C100 100 µg -

3 - 9 business days*

286.00€
 
Recognizes mouse progranulin. Detects a band of about 90kDa by Western blot. Weakly cross-reacts... more
Product information "Anti-Progranulin (mouse)"
Recognizes mouse progranulin. Detects a band of about 90kDa by Western blot. Weakly cross-reacts with human progranulin. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the PGRN gene were found in cases of frontotemporal degeneration (FTLD). In addition, PGRN has also been linked to tumorigenesis. Progranulin is a biomarker for FTLD, other types of Alzheimer's Disease (AD) and potentially for MCI (Mild Cognitive Impairment). Additionally, PGRN is described as a new ligand of TNF receptors and a potential therapeutic against inflammatory disease like arthritis.
Keywords: Proepithelin, PEPI, PC Cell-derived Growth Factor
Supplier: AdipoGen Life Sciences
Supplier-Nr: AG-25A-0093

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rat
Species reactivity: mouse
Immunogen: Recombinant mouse progranulin.
MW: 90 kD
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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