Anti-PRKG2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA007386.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA007386.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Crucial regulator of intestinal secretion and bone growth. Phosphorylates and... more

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Product information "Anti-PRKG2"

Protein function: Crucial regulator of intestinal secretion and bone growth. Phosphorylates and activates CFTR on the plasma membrane. Plays a key role in intestinal secretion by regulating cGMP-dependent translocation of CFTR in jejunum. Acts downstream of NMDAR to activate the plasma membrane accumulation of GRIA1/GLUR1 in synapse and increase synaptic plasticity. Phosphorylates GRIA1/GLUR1 at Ser-863. Acts as regulator of gene expression and activator of the extracellular signal-regulated kinases MAPK3/ERK1 and MAPK1/ERK2 in mechanically stimulated osteoblasts. Under fluid shear stress, mediates ERK activation and subsequent induction of FOS, FOSL1/FRA1, FOSL2/FRA2 and FOSB that play a key role in the osteoblast anabolic response to mechanical stimulation. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 96% and to rat: 96%

Keywords:	Anti-cGK2, Anti-cGKII, Anti-cGK 2, Anti-PRKG2, Anti-PRKGR2, EC=2.7.11.12, Anti-cGMP-dependent protein kinase 2, Anti-cGMP-dependent protein kinase II
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA007386

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: REYHLKELRE QLSKQTVAIA ELTEELQNKC IQLNKLQDVV HMQGGSPLQA SPDKVPLEVH RKTSGLVSLH SRRGAKAGVS AEPTTRTYDL NKPPEFSFEK ARVRKDSSEK KLITDALNKN QFLKRLDPQQ IKDMVE (ATA-APrEST86393)