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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-R32679 | 100 µg | - | - |
3 - 10 business days* |
755.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.5mg/ml if reconstituted with 0.2ml sterile DI water. cAMP-dependent protein kinase type I-alpha... more
Product information "Anti-PRKAR1A"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. cAMP-dependent protein kinase type I-alpha regulatory subunit is an enzyme that in humans is encoded by the PRKAR1A gene. This protein encoded by this gene was found to be a tissue-specific extinguisher that down-regulates the expression of seven liver genes in hepatoma x fibroblast hybrids. Mutations in this gene cause Carney complex (CNC). This gene can fuse to the RET protooncogene by gene rearrangement and form the thyroid tumor-specific chimeric oncogene known as PTC2. A nonconventional nuclear localization sequence (NLS) has been found for this protein which suggests a role in DNA replication via the protein serving as a nuclear transport protein for the second subunit of the Replication Factor C (RFC40). Several alternatively spliced transcript variants encoding two different isoforms have been observed. Protein function: Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. [The UniProt Consortium]
Keywords: | Anti-TSE1, Anti-PKR1, Anti-PRKAR1A, Anti-Tissue-specific extinguisher 1, Anti-cAMP-dependent protein kinase type I-alpha regulatory subunit, PRKAR1A Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | R32679 |
Properties
Application: | WB, IHC (paraffin) |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, rat |
Immunogen: | Amino acids E2-E81 from the human protein |
Format: | Purified |
Database Information
KEGG ID : | K04739 | Matching products |
UniProt ID : | P10644 | Matching products |
Gene ID : | GeneID 5573 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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