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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-R30484 | 100 µg | - | - |
3 - 10 business days* |
755.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Pleiotrophin(PTN) also known as... more
Product information "Anti-Pleiotrophin"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Pleiotrophin(PTN) also known as heparin-binding brain mitogen(HBBM) or heparin-binding growth factor 8(HBGF-8) or neurite growth-promoting factor 1(NEGF1) or heparin affinity regulatory peptide(HARP) or heparin binding growth associated molecule(HB-GAM) is a protein that in humans is encoded by the PTN gene. PTN is the first member of a family of developmentally regulated cytokines. The PTN gene is mapped to 7q33-q34. A mutant PTN that contained only the first N-terminal 40 amino acids was a dominant negative. Pleiotrophin is expressed in the central and peripheral nervous system and also in several non-neural tissues, notably lung, kidney, gut and bone. Pleiotrophin binds to cell-surface nucleolin as a low affinity receptor. This binding can inhibit HIV infection. Protein function: Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti- apoptotic signaling of PTN and regulation of cell proliferation. [The UniProt Consortium]
Keywords: | Anti-PTN, Anti-HBBM, Anti-HBNF1, Anti-OSF-1, Anti-HB-GAM, Anti-HBNF-1, Anti-HBGF-8, Anti-Pleiotrophin, Anti-Osteoblast-specific factor 1, Anti-Heparin-binding brain mitogen, Anti-Heparin-binding growth factor 8, Pleiotrophin Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | R30484 |
Properties
Application: | WB, IHC (paraffin) |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | An amino acid sequence from the C-terminus of human Pleiotrophin (QAESKKKKKEGKKQEKMLD) was used as the immunogen for this Pleiotrophin antibody (100% homologous in human, mouse and rat). |
Format: | Purified |
Database Information
KEGG ID : | K16642 | Matching products |
UniProt ID : | P21246 | Matching products |
Gene ID : | GeneID 5764 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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