Anti-PLCD4

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA038139.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA038139.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2... more

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Product information "Anti-PLCD4"

Protein function: Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores. Required for acrosome reaction in sperm during fertilization, probably by acting as an important enzyme for intracellular Ca(2+) mobilization in the zona pellucida-induced acrosome reaction. May play a role in cell growth. Modulates the liver regeneration in cooperation with nuclear PKC. Overexpression up-regulates the Erk signaling pathway and proliferation. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 76% and to rat: 73%

Keywords:	Anti-hPLCD4, Anti-PLC-delta-4, Anti-Phospholipase C-delta-4, Anti-Phosphoinositide phospholipase C-delta-4, Anti-1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA038139

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: MASLLQDQLT TDQDLLLMQE GMPMRKVRSK SWKKLRYFRL QNDGMTVWHA RQARGSAKPS FSISDVETIR NGHDSELL (ATA-APrEST87276)