Anti-PLAG1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA072290.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA072290.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Transcription factor whose activation results in up- regulation of target... more

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Product information "Anti-PLAG1"

Protein function: Transcription factor whose activation results in up- regulation of target genes, such as IGFII, leading to uncontrolled cell proliferation: when overexpressed in cultured cells, higher proliferation rate and transformation are observed. Other target genes such as CRLF1, CRABP2, CRIP2, PIGF are strongly induced in cells with PLAG1 induction. Proto-oncogene whose ectopic expression can trigger the development of pleomorphic adenomas of the salivary gland and lipoblastomas. Overexpression is associated with up-regulation of IGFII, is frequently observed in hepatoblastoma, common primary liver tumor in childhood. Cooperates with CBFB-MYH11, a fusion gene important for myeloid leukemia. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 98% and to rat: 97%

Keywords:	Anti-PLAG1, Anti-Zinc finger protein PLAG1, Anti-Pleiomorphic adenoma gene 1 protein
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA072290

Properties

Application:	ICC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: EPVDFLDPFT CNVSVPIKDE LLPVMSLPSS ELLSKPFTNT LQLNLYNTPF QSMQSSGSAH Q (ATA-APrEST93071)