Anti-phospho-CDH5 (Tyr731)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
CSB-PA868788.100	100 µl		-	-	10 - 14 business days*		320.00€

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Protein function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially... more

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Product information "Anti-phospho-CDH5 (Tyr731)"

Protein function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types (PubMed:21269602). This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton (PubMed:10861224). Acts in concert with KRIT1 and MPP5 to establish and maintain correct endothelial cell polarity and vascular lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B (PubMed:20332120). Required for activation of PRKCZ and for the localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction (PubMed:20332120). [The UniProt Consortium]

Keywords:	Anti-phospho-CDH5, Anti-phospho-CD144, Anti-phospho-Cadherin-5, Anti-phospho-VE-cadherin, Anti-phospho-7B4 antigen, Anti-phospho-Vascular endothelial cadherin, Phospho-CDH5 (Tyr731) Antibody
Supplier:	Cusabio
Supplier-Nr:	PA868788

Properties

Application:	ELISA, WB
Antibody Type:	Polyclonal
Conjugate:	No
Species reactivity:	human
Immunogen:	Peptide sequence around phosphorylation site of Tyrosine731 (H-I-Y(p)-G-Y) derived from Human VE-Cadherin.