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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ATA-HPA029579.25 | 25 µl | - |
7 - 10 business days* |
335.00€
|
|||
ATA-HPA029579.100 | 100 µl | - |
7 - 10 business days* |
446.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Scaffold protein of the presynaptic cytomatrix at the active zone (CAZ) which... more
Product information "Anti-PCLO"
Protein function: Scaffold protein of the presynaptic cytomatrix at the active zone (CAZ) which is the place in the synapse where neurotransmitter is released. After synthesis, participates in the formation of Golgi-derived membranous organelles termed Piccolo-Bassoon transport vesicles (PTVs) that are transported along axons to sites of nascent synaptic contacts. At the presynaptic active zone, regulates the spatial organization of synaptic vesicle cluster, the protein complexes that execute membrane fusion and compensatory endocytosis. Organizes as well the readily releasable pool of synaptic vesicles and safeguards a fraction of them to be not immediately available for action potential-induced release. Functions also in processes other than assembly such as the regulation of specific presynaptic protein ubiquitination by interacting with SIAH1 or the regulation of presynaptic autophagy. Mediates also synapse to nucleus communication leading to reconfiguration of gene expression by associating with the transcriptional corepressor CTBP1 and by subsequently reducing the size of its pool available for nuclear import. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 70% and to rat: 72%
Keywords: | Anti-Aczonin, Anti-Protein piccolo |
Supplier: | Atlas Antibodies |
Supplier-Nr: | HPA029579 |
Properties
Application: | ICC, IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: PITTLDSITT VYTEPVDMIT KFEDSEEISS STYFPGSIID YPEEISVSLD RTAPPDGRAS ADHIVISLSD MASSIIESVV PKPEGPVADT VSTDLLISEK DPVKKAKKET GNGIILEVLE A (ATA-APrEST72538) |
Database Information
KEGG ID : | K16882 | Matching products |
UniProt ID : | Q9Y6V0 | Matching products |
Gene ID | GeneID 27445 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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