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Save 30% on all primary antibodies by Arigo Biolaboratories!
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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Discount | Price |
---|---|---|---|---|---|---|---|---|
ARG44379.100 | 100 µl | - | - |
6 - 14 business days* |
30 %
|
624.00€
436.80€ |
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: This is one of the 2 subunits of the biotin-dependent propionyl-CoA carboxylase... more
Product information "Anti-PCCA"
Protein function: This is one of the 2 subunits of the biotin-dependent propionyl-CoA carboxylase (PCC), a mitochondrial enzyme involved in the catabolism of odd chain fatty acids, branched-chain amino acids isoleucine, threonine, methionine, and valine and other metabolites (PubMed:8434582, PubMed:6765947). Propionyl-CoA carboxylase catalyzes the carboxylation of propionyl-CoA/propanoyl-CoA to D-methylmalonyl- CoA/(S)-methylmalonyl-CoA (PubMed:8434582, PubMed:6765947, PubMed:10101253). Within the holoenzyme, the alpha subunit catalyzes the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain, while the beta subunit then transfers the carboxyl group from carboxylated biotin to propionyl-CoA. Propionyl-CoA carboxylase also significantly acts on butyryl-CoA/butanoyl-CoA, which is converted to ethylmalonyl-CoA/(2S)- ethylmalonyl-CoA at a much lower rate (PubMed:6765947). Other alternative minor substrates include (2E)-butenoyl-CoA/crotonoyl-CoA. [The UniProt Consortium]
Keywords: | Anti-PCCase subunit alpha, Anti-PCCase subunit alpha, Anti-Propanoyl-CoA:carbon dioxide ligase subunit alpha, Anti-Propanoyl-CoA:carbon dioxide ligase subunit alpha, Anti-Propionyl-CoA carboxylase alpha chain, mitochondrial, Anti-Propionyl-CoA carboxylase |
Supplier: | Arigo Biolaboratories |
Supplier-Nr: | ARG44379 |
Properties
Application: | IHC (paraffin), WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 449-728 of human PCCA |
MW: | 80 kD |
Format: | Affinity Purified |
Database Information
KEGG ID : | K01965 | Matching products |
UniProt ID : | P05165 | Matching products |
Gene ID : | GeneID 5095 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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