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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
P3105-75E.100 | 100 µg | - | - |
3 - 19 business days* |
1,007.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Proteinase-Activated Receptor 2 (PAR-2) is a proteinase activated 7-transmembrane... more
Product information "Anti-PAR2 (Proteinase Activated Receptor 2)"
Proteinase-Activated Receptor 2 (PAR-2) is a proteinase activated 7-transmembrane G-protein-coupled receptor. Human PAR-2 contains a cleavage site for trypsin, mast cell tryptase or coagulation factor VIIa or Xa, 11 amino acids (aa) C-terminal to the signal sequence. Cleavage creates a tethered ligand that activates the 361aa receptor. PAR-2 is expressed in kidney, pancreas, stomach, intestine, airway, skin, bladder and brain, activation stimulates release of inflammatory and nociceptive mediators. PAR-2 is downregulated by ubiquination, endocytosis and degradation. Mature human PAR-2 shows 78% amino acid identity with mouse PAR-2 over the extracellular portions. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilutions: Flow Cytometry: 2.5ug/10e6 cells tested with HT-29 human colon adenocarcinoma cell line, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: | Anti-F2RL1, Anti-PAR-2, Anti-GPR11, Anti-Thrombin receptor-like 1, Anti-G-protein coupled receptor 11, Anti-Proteinase-activated receptor 2, Anti-Coagulation factor II receptor-like 1, Anti-Proteinase-activated receptor 2, alternate cleaved 1 |
Supplier: | United States Biological |
Supplier-Nr: | P3105-75E |
Properties
Application: | FC |
Antibody Type: | Monoclonal |
Clone: | 7H40 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | NS0 cells transfected with human PAR-2, Accession # P55085 |
Format: | Affinity Purified |
Database Information
KEGG ID : | K04234 | Matching products |
UniProt ID : | P55085 | Matching products |
Gene ID : | GeneID 2150 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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