Anti-PAK3

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG42665.100	100 µl		-	-	6 - 14 business days*		624.00€

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Protein function: Serine/threonine protein kinase that plays a role in a variety of different... more

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Product information "Anti-PAK3"

Protein function: Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, or cell cycle regulation. Plays a role in dendrite spine morphogenesis as well as synapse formation and plasticity. Acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates MAPK4 and MAPK6 and activates the downstream target MAPKAPK5, a regulator of F-actin polymerization and cell migration. Additionally, phosphorylates TNNI3/troponin I to modulate calcium sensitivity and relaxation kinetics of thin myofilaments. May also be involved in early neuronal development. [The UniProt Consortium]

Keywords:	Anti-PAK3, Anti-OPHN3, Anti-PAK-3, Anti-Beta-PAK, EC=2.7.11.1, Anti-Oligophrenin-3, Anti-p21-activated kinase 3, Anti-Serine/threonine-protein kinase PAK 3
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG42665

Properties

Application:	IHC (paraffin), WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Synthetic peptide within aa. 1-50 of Human PAK3
MW:	62 kD
Format:	Affinity Purified