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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A301-719A-T | 10 µl (10 µg) | - |
2 - 8 business days* |
164.00€
|
|||
A301-719A | 100 µl (100 µg) | - |
2 - 8 business days* |
588.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Plays a role in the process of neurogenesis. Required throughout embryonic... more
Product information "Anti-NUMBL"
Protein function: Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of embryonic neurogenesis. Also required postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. Negative regulator of NF-kappa-B signaling pathway. The inhibition of NF- kappa-B activation is mediated at least in part, by preventing MAP3K7IP2 to interact with polyubiquitin chains of TRAF6 and RIPK1 and by stimulating the 'Lys-48'-linked polyubiquitination and degradation of TRAF6 in cortical neurons. [The UniProt Consortium]
Keywords: | Anti-NUMBL, Anti-Numb-R, Anti-Numb-like protein, Anti-Numb-related protein |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A301-719A |
Properties
Application: | WB, IP |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human (Expected: chimpanzee) |
Immunogen: | synthetic peptide. The epitope recognized by A301-719A-T maps to a region between residue 545 and 595 of human numb (Drosophila) homolog-like using the numbering given in entry NP_004747.1 (GeneID 9253). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K06057 | Matching products |
UniProt ID : | Q9Y6R0 | Matching products |
Gene ID : | GeneID 9253 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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