Anti-NR5A2

Anti-NR5A2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-67702.60 60 µl -

7 - 16 business days*

198.00€
E-AB-67702.120 120 µl -

7 - 16 business days*

317.00€
E-AB-67702.200 200 µl -

7 - 16 business days*

525.00€
 
The protein encoded by this gene is a DNA-binding zinc finger transcription factor and is a... more
Product information "Anti-NR5A2"
The protein encoded by this gene is a DNA-binding zinc finger transcription factor and is a member of the fushi tarazu factor-1 subfamily of orphan nuclear receptors. The encoded protein is involved in the expression of genes for hepatitis B virus and cholesterol biosynthesis, and may be an important regulator of embryonic development. Protein function: Nuclear receptor that acts as a key metabolic sensor by regulating the expression of genes involved in bile acid synthesis, cholesterol homeostasis and triglyceride synthesis. Together with the oxysterol receptors NR1H3/LXR-alpha and NR1H2/LXR-beta, acts as an essential transcriptional regulator of lipid metabolism. Plays an anti- inflammatory role during the hepatic acute phase response by acting as a corepressor: inhibits the hepatic acute phase response by preventing dissociation of the N-Cor corepressor complex (PubMed:20159957). Binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. May be responsible for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development. Activates the transcription of CYP2C38. [The UniProt Consortium]
Keywords: Anti-B1F, Anti-hB1F, Anti-NR5A2, Anti-LRH-1, Anti-B1-binding factor, Anti-Liver receptor homolog 1, Anti-CYP7A promoter-binding factor, Anti-Hepatocytic transcription factor, Anti-Alpha-1-fetoprotein transcription factor, NR5A2 Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-67702

Properties

Application: IF
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Recombinant fusion protein of human NR5A2 (NP_003813.1).

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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Anti-NR5A2 Anti-NR5A2
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-30 %
Discount Promotion
Anti-NR5A2 Anti-NR5A2
520.00€ * 364.00€ *
Anti-NR5A2 Anti-NR5A2
From 198.00€ *
Anti-NR5A2 Anti-NR5A2
From 198.00€ *
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