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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A302-083A-T | 10 µl (2 µg) | - |
2 - 8 business days* |
164.00€
|
|||
A302-083A | 100 µl | - |
2 - 8 business days* |
588.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1... more
Product information "Anti-Notch2"
Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in bone remodeling and homeostasis. In collaboration with RELA/p65 enhances NFATc1 promoter activity and positively regulates RANKL-induced osteoclast differentiation. Positively regulates self-renewal of liver cancer cells (PubMed:25985737). [The UniProt Consortium]
Keywords: | Anti-NOTCH2 |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A302-083A |
Properties
Application: | WB, IP, IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human (Expected: horse, panda, rhesus monkey, gorilla, black-handed spider monkey, crab-eating macaque, hamadryas baboon, kloss's gibbon, european domestic ferret, northern white-cheeked gibbon, red-chested mustached tamarin) |
Immunogen: | synthetic peptide. The epitope recognized by A302-083A-T maps to a region between residue 2250 and 2300 of human neurogenic locus notch homolog protein 2 using the numbering given in entry NP_077719.2 (GeneID 4853). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K20994 | Matching products |
UniProt ID : | Q04721 | Matching products |
Gene ID : | GeneID 4853 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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