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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
600-401-C87 | 10 µg | - | - |
6 - 10 business days* |
684.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Anti-NMDA 2B antibody is directed against NMDA receptor protein. The antibody was affinity... more
Product information "Anti-NMDA NR2B Subunit"
Anti-NMDA 2B antibody is directed against NMDA receptor protein. The antibody was affinity purified from monospecific antiserum by immunoaffinity purification. The antibody Recognizes human, mouse and rat forms of the NR2B subunits of NMDAR. Immunolabeling is blocked by pre-adsorption of antibody with the fusion protein used to generate the antibody. No reactivity towards the NR2A and NR2C subunits was seen. Protein function: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2 influx through them, resulting in an irreversible neuronal death. [The UniProt Consortium]
Keywords: | Anti-NR2B, Anti-GluN2B, Anti-Grin2b, Anti-NMDAR2B, Anti-Glutamate receptor ionotropic, NMDA 2B, Anti-N-methyl D-aspartate receptor subtype 2B, Anti-Glutamate [NMDA] receptor subunit epsilon-2 |
Supplier: | Rockland Immunochemicals |
Supplier-Nr: | 600-401-C87 |
Properties
Application: | IHC, IP, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | rat, mouse, human |
Immunogen: | fusion protein from the C-terminal region NR2B subunit. |
Format: | Purified |
Database Information
KEGG ID : | K05210 | Matching products |
UniProt ID : | Q00960 | Matching products |
Gene ID | GeneID 24410 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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