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![Anti-NKIRAS1, clone NRAS285](https://www.biomol.com/media/image/ce/90/79/NSJ-N1127-25UG_600x600.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-N1127-25UG | 25 µg | - | - |
3 - 10 business days* |
317.00€
|
||
NSJ-N1127-100UG | 100 µg | - | - |
3 - 10 business days* |
622.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. NKIRAS1 is part of the Ras family... more
Product information "Anti-NKIRAS1, clone NRAS285"
0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. NKIRAS1 is part of the Ras family and GTPase superfamily of proteins. Unlike other family members which have a glycine and glutamine residue at positions 13 and 65, NKIRAS1 (and 2) has leucines in these positions.NKIRAS1 is a regulator of NF-kB activity via its inhibition of IkB (NFKBIB) degradation. IkB complexes with NF-kB, preventing nuclear translocation and subsequent signaling. By preventing or reducing IkB degradation, NKIRAS1 blocks NF-kB signaling activity. Protein function: Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB. [The UniProt Consortium]
Keywords: | Anti-KBRAS1, Anti-NKIRAS1, Anti-KappaB-Ras1, Anti-Kappa B-Ras protein 1, Anti-I-kappa-B-interacting Ras-like protein 1, Anti-NF-kappa-B inhibitor-interacting Ras-like protein 1, NKIRAS1 Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | N1127 |
Properties
Application: | WB |
Antibody Type: | Monoclonal |
Clone: | NRAS285 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human, mouse, rat |
Immunogen: | A recombinant protein fragment from the central region of NKIRAS1 was used as the immunogen for this antibody. |
Format: | Purified |
Database Information
KEGG ID : | K17197 | Matching products |
UniProt ID : | Q9NYS0 | Matching products |
Gene ID | GeneID 28512 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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