Anti-NIK (Nck-interacting kinase)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
NSJ-F50948-0.08ML	80 µl		-	-	3 - 10 business days*		350.00€
NSJ-F50948-0.4ML	400 µl		-	-	3 - 10 business days*		755.00€

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In 1X PBS, pH 7.4, with 0.09% sodium azide. HGK/NIK, a member of the STE20 subfamily of Ser/Thr... more

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Product information "Anti-NIK (Nck-interacting kinase)"

In 1X PBS, pH 7.4, with 0.09% sodium azide. HGK/NIK, a member of the STE20 subfamily of Ser/Thr protein kinases, may play a role in the response to environmental stress and cytokines such as TNF-alpha. It appears to act upstream of the JUN N-terminal pathway. This protein is thought to interact with the SH3 domain of the adapter proteins Nck. HGK/NIK binds, via its CNH regulatory domain, to the N-terminal region of SPG3A. Expression appears to be ubiquitous, expressed in all tissue types examined. Isoform 5 appears to be more abundant in the brain, and isoform 4 is predominant in the liver, skeletal muscle and placenta. Protein function: Serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. Appears to act upstream of the JUN N-terminal pathway. Phosphorylates SMAD1 on Thr-322. [The UniProt Consortium]

Keywords:	Anti-HGK, Anti-MAP4K4, Anti-MEKKK 4, EC=2.7.11.1, Anti-MEK kinase kinase 4, Anti-Nck-interacting kinase, Anti-HPK/GCK-like kinase HGK, Anti-MAPK/ERK kinase kinase kinase 4, Anti-Mitogen-activated protein kinase kinase kinase kinase 4, NIK Antibody (Nck-in
Supplier:	NSJ Bioreagents
Supplier-Nr:	F50948

Properties

Application:	WB, ELISA
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	A portion of amino acids 618-649 from the human protein was used as the immunogen for this NIK antibody.
Format:	Purified