Anti-NF2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A300-578A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A300-578A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a... more

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Product information "Anti-NF2"

Protein function: Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP/DCAF1 E3 ubiquitin-protein ligase complex. [The UniProt Consortium]

Keywords:	Anti-NF2, Anti-SCH, Anti-Merlin, Anti-Schwannomin, Anti-Schwannomerlin, Anti-Neurofibromin-2, Anti-Moesin-ezrin-radixin-like protein
Supplier:	Bethyl Laboratories
Supplier-Nr:	A300-578A

Properties

Application:	WB, IP, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: mouse)
Immunogen:	synthetic peptide. The epitope recognized by A300-578A-T maps to a region between residue 550 and the C-terminus (residue 595) of human Neurofibromin 2 using the numbering given in entry NP_000259.1 (GeneID 4771). This epitope is common to NF2 isoforms 1 and 9 (Mer162).
Format:	Antigen Affinity Purified