Anti-Neurofibromin (NF1, WSS, NFNS, VRNF, NF, Neurofibromin 1, neurofibromatosis, type I, von Reckli

Neurofibromin is a product of the tumor suppressor gene, Neurofibromatosis type I. Neurofibromin is known to have GTPase activity that modulates the ras pathway. The absence of or alteration of the neurofibromin protein may lead to Neurofibromatosis disease. This protein has not been purified, therefore, most of the information regarding this protein has been deduced from homology analysis of its gene sequence. Application(s): ELISA, affinity chromatography, Western Blot, Immunoprecipitation. , Recommended Dilution:, Western Blot: 2-5 ug/ml, Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.