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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ATA-HPA020259.100 | 100 µl | - |
7 - 10 business days* |
446.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Essential component of the NELF complex, a complex that negatively regulates... more
Product information "Anti-NELFB"
Protein function: Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II (PubMed:12612062). The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex (PubMed:10199401). May be able to induce chromatin unfolding (PubMed:11739404). Essential for early embryogenesis, plays an important role in maintaining the undifferentiated state of embryonic stem cells (ESCs) by preventing unscheduled expression of developmental genes. Plays a key role in establishing the responsiveness of stem cells to developmental cues, facilitates plasticity and cell fate commitment in ESCs by establishing the appropriate expression level of signaling molecules. Supports the transcription of genes involved in energy metabolism in cardiomyocytes, facilitates the association of transcription initiation factors with the promoters of the metabolism- related genes. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 100% and to rat: 100%
Keywords: | Anti-NELFB, Anti-NELF-B, Anti-Cofactor of BRCA1, Anti-Negative elongation factor B |
Supplier: | Atlas Antibodies |
Supplier-Nr: | HPA020259 |
Properties
Application: | ICC, IHC, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: KETLTNCTEP LKAIEQFQTE NGVLLPSLQS ALPFLDLHGT PRLEFHQSVF DELRDKLLER VSAIASEGKA EERYKKLED (ATA-APrEST75421) |
Database Information
KEGG ID : | K15180 | Matching products |
UniProt ID : | Q8WX92 | Matching products |
Gene ID : | GeneID 25920 | Matching products |
Protein Atlas Nr. : | ENSG00000188986 |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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