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![Anti-NAG-1 (H variant specific), Peroxidase conjugated](https://www.biomol.com/media/image/51/82/75/600-403-B08_600x600.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
600-403-B08 | 100 µg | - | - |
6 - 10 business days* |
641.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Non-steroidal anti-inflammatory drug (NSAID) activated gene (NAG-1) is a member of the... more
Product information "Anti-NAG-1 (H variant specific), Peroxidase conjugated"
Non-steroidal anti-inflammatory drug (NSAID) activated gene (NAG-1) is a member of the transforming growth factor-beta (TGF-beta) superfamily. NAG-1 is expressed in human placenta, prostate and colon. It possesses antitumorigenic and proapoptotic activities. NAG-1 expression is dramatically increased in inflammation, injury and malignancy. Increase of NAG-1 expression is a feature of many cancers including breast, colon, pancreas and prostate. In a number of studies, NAG-1 expression was increased by a number of NSAIDs. This increase in expression may correlate with the chemopreventive effect NSAIDs seem to have with certain cancers. NAG-1 expression is also induced by PPAR gamma ligands and by several dietary compounds such as conjugated linoleic acids (CLAs), naturally occurring fatty acids in ruminant food products, indoles, epicatechin gallate, and genistein. Induced expression of NAG-1 results in stimulation of apoptosis and inhibition of cell growth. Inhibition of NAG-1 induced expression by small interference RNA (siRNA) results in repression of induced apoptosis. NAG-1 expression is regulated by a numbers of transcription factors such as ERG-1 and Sp1. EGR-1 may be necessary for NSAID-induced NAG-1 expression.
Keywords: | Anti-MIC1, Anti-MIC-1, Anti-NRG-1, Anti-GDF15, Anti-NAG-1, Anti-GDF-15, Anti-Placental TGF-beta, Anti-NSAID-regulated gene 1 protein, Anti-NSAID-activated gene 1 protein, Anti-Prostate differentiation factor, Anti-Macrophage inhibitory cytokine 1 |
Supplier: | Rockland Immunochemicals |
Supplier-Nr: | 600-403-B08 |
Properties
Application: | ELISA, WB |
Antibody Type: | Polyclonal |
Conjugate: | HRP |
Host: | Rabbit |
Species reactivity: | human (Expected: chimpanzee, macaque) |
Immunogen: | synthetic peptide corresponding to a region near the amino terminal end of human NAG-1 protein |
Format: | Purified |
Database Information
KEGG ID : | K05504 | Matching products |
UniProt ID : | Q99988 | Matching products |
Gene ID | GeneID 9518 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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