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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ARG59154.100 | 100 µl | - | - |
6 - 14 business days* |
658.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by... more
Product information "Anti-NAE1 / APPBP1"
Protein function: Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Necessary for cell cycle progression through the S-M checkpoint. Overexpression of NAE1 causes apoptosis through deregulation of NEDD8 conjugation. [The UniProt Consortium]
| Keywords: | Anti-NAE1, Anti-HPP1, Anti-APPBP1, Anti-APP-BP1, Anti-Proto-oncogene protein 1, Anti-Amyloid protein-binding protein 1, Anti-NEDD8-activating enzyme E1 regulatory subunit, Anti-Amyloid beta precursor protein-binding protein 1, 59 kDa |
| Supplier: | Arigo Biolaboratories |
| Supplier-Nr: | ARG59154 |
Properties
| Application: | WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
| Immunogen: | Recombinant fusion protein corresponding to aa. 1-220 of Human NAE1 (NP_003896.1) |
| MW: | 60 kD |
| Format: | Affinity Purified |
Database Information
| KEGG ID : | K04532 | Matching products |
| UniProt ID : | Q13564 | Matching products |
| Gene ID : | GeneID 8883 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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