Anti-NAE1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA042041.25	25 µl		-		7 - 10 business days*		239.00€
ATA-HPA042041.100	100 µl		-		7 - 10 business days*		477.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by... more

Close menu

Product information "Anti-NAE1"

Protein function: Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Necessary for cell cycle progression through the S-M checkpoint. Overexpression of NAE1 causes apoptosis through deregulation of NEDD8 conjugation. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 97% and to rat: 98%

Keywords:	Anti-HPP1, Anti-NAE1, Anti-APPBP1, Anti-APP-BP1, Anti-Proto-oncogene protein 1, Anti-Amyloid protein-binding protein 1, Anti-NEDD8-activating enzyme E1 regulatory subunit, Anti-Amyloid beta precursor protein-binding protein 1, 59 kDa
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA042041

Properties

Application:	WB, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: KPFPELREHF QSYDLDHMEK KDHSHTPWIV IIAKYLAQWY SETNGRIPKT YKEKEDFRDL IRQGILKNEN GAPEDEENFE EAIKNVNTAL NTTQIPSSIE DIFNDDR (ATA-APrEST82217)