Anti-NAAA / N-acylethanolamine-hydrolyzing acid amidase

0.5mg/ml if reconstituted with 0.2ml sterile DI water. N-acylethanolamine-hydrolyzing acid amidase, also called ASAHL and PLT, is an enzyme that in humans is encoded by the NAAA gene. Enables N-(long-chain-acyl)ethanolamine deacylase activity, N-acylsphingosine amidohydrolase activity, and fatty acid amide hydrolase activity. Involved in several processes, including N-acylethanolamine metabolic process, N-acylphosphatidylethanolamine metabolic process, and sphingosine metabolic process. Located in lysosome. Is extrinsic component of membrane. Protein function: Degrades bioactive fatty acid amides to their corresponding acids, with the following preference: N-palmitoylethanolamine > N- myristoylethanolamine > N-lauroylethanolamine = N-stearoylethanolamine > N-arachidonoylethanolamine > N-oleoylethanolamine (PubMed:15655246, PubMed:17980170, PubMed:18793752, PubMed:30301806, PubMed:22825852). Also exhibits weak hydrolytic activity against the ceramides N- lauroylsphingosine and N-palmitoylsphingosine (PubMed:15655246). [The UniProt Consortium]