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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-V3663SAF-100UG | 100 µg | - | - |
3 - 10 business days* |
752.00€
|
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
1 mg/ml in 1X PBS, BSA free, sodium azide free. MyoD, or MYOD1, is one of the earliest markers of... more
Product information "Anti-MyoD1, clone MYOD1/2075R"
1 mg/ml in 1X PBS, BSA free, sodium azide free. MyoD, or MYOD1, is one of the earliest markers of myogenic commitment. MyoD is expressed at extremely low and essentially undetectable levels in quiescent satellite cells, but expression of MyoD is activated in response to exercise or muscle tissue damage. The effect of MyoD on satellite cells is dose-dependent, high MyoD expression represses cell renewal, promotes terminal differentiation and can induce apoptosis. Although MyoD marks myoblast commitment, muscle development is not dramatically ablated in mouse mutants lacking the MyoD gene. This is likely due to functional redundancy from Myf5 and/or Mrf4. Nevertheless, the combination of MyoD and Myf5 is vital to the success of myogenesis. [Wiki] Protein function: Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins. [The UniProt Consortium]
Keywords: | Anti-MYOD1, Anti-Myf-3, Anti-bHLHc1, Anti-BHLHC1, Anti-Myogenic factor 3, Anti-Myoblast determination protein 1, Anti-Class C basic helix-loop-helix protein 1, MyoD1 Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | V3663SAF |
Properties
Application: | IHC (paraffin) |
Antibody Type: | Monoclonal |
Clone: | MYOD1/2075R |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Recombinant human protein was used as the immunogen for this recombinant MyoD antibody. |
Format: | Purified |
Database Information
KEGG ID : | K09064 | Matching products |
UniProt ID : | P15172 | Matching products |
Gene ID : | GeneID 4654 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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