Anti-MUC6, clone SPM598

Anti-MUC6, clone SPM598
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V2742IHC-7ML 7 ml - -

3 - 10 business days*

752.00€
 
Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only*. The... more
Product information "Anti-MUC6, clone SPM598"
Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only*. The MUC6 gastric mucin is a secreted glycoprotein that plays an essential role in epithelial cyto-protection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. Mucin 6 expression is highest in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. In gastric cancer, Mucin 6 has an altered expression. In normal stomach, Mucin 6 is associated with Lewis type 2, Mucin 6 is also expressed in gastric metaplasia, duodenum and pancreas. Mucin 6 is a secretory mucin, located in the deeper mucosal folds of human gall bladder, and its expression is altered with increasing degrees of inflammation. Protein function: May provide a mechanism for modulation of the composition of the protective mucus layer related to acid secretion or the presence of bacteria and noxious agents in the lumen. Plays an important role in the cytoprotection of epithelial surfaces and are used as tumor markers in a variety of cancers. May play a role in epithelial organogenesis. [The UniProt Consortium]
Keywords: Anti-MUC6, Anti-MUC-6, Anti-Mucin-6, Anti-Gastric mucin-6, MUC6 Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V2742IHC

Properties

Application: IHC (paraffin)
Antibody Type: Monoclonal
Clone: SPM598
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: A synthetic peptide of the gastric Mucin 6 tandem repeat sequence
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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