Anti-MRC2 / Endo180

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG66607.100	100 µg		-	-	6 - 14 business days*		616.00€

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Protein function: May play a role as endocytotic lectin receptor displaying calcium-dependent... more

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Product information "Anti-MRC2 / Endo180"

Protein function: May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs). [The UniProt Consortium]

Keywords:	Anti-MRC2, Anti-CD280, Anti-CLEC13E, Anti-Endocytic receptor 180, Anti-UPAR-associated protein, Anti-C-type mannose receptor 2, Anti-Macrophage mannose receptor 2, Anti-Urokinase receptor-associated protein, Anti-C-type lectin domain family 13 member E
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG66607

Properties

Application:	ICC, IF, IHC (paraffin), WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Synthetic peptide within aa. 90-170 of Human MRC2 / Endo180
MW:	167 kD
Format:	Antigen Affinity Purified