Anti-MITF, clone 21D1418

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
200-301-H93	100 µg		-	-	6 - 10 business days*		756.00€

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Anti-MITF Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest... more

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Product information "Anti-MITF, clone 21D1418"

Anti-MITF Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with MITF from Human, Rat, and Mouse based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-MITF from other sources has not been determined. Protein function: Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences (E-boxes) (5'- CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest- derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium. [The UniProt Consortium]

Keywords:	Anti-MITF, Anti-BHLHE32, Anti-bHLHe32, Anti-Class E basic helix-loop-helix protein 32, Anti-Microphthalmia-associated transcription factor
Supplier:	Rockland Immunochemicals
Supplier-Nr:	200-301-H93

Properties

Application:	WB
Antibody Type:	Monoclonal
Clone:	21D1418
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	synthetic peptide corresponding to internal amino acids with human MITF protein.
Format:	Purified