Anti-MITF, clone 1607CT834.207.47

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Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Discount	Price
ARG41351.100	100 µl		-	-	6 - 14 business days*		30 %	624.00€ 436.80€

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Protein function: Transcription factor that regulates the expression of genes with essential... more

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Product information "Anti-MITF, clone 1607CT834.207.47"

Protein function: Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to M-boxes (5'-TCATGTG-3') and symmetrical DNA sequences (E-boxes) (5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium. [The UniProt Consortium]

Keywords:	Anti-MITF, Anti-BHLHE32, Anti-bHLHe32, Anti-Class E basic helix-loop-helix protein 32, Anti-Microphthalmia-associated transcription factor
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG41351

Properties

Application:	WB
Antibody Type:	Monoclonal
Clone:	1607CT834.207.47
Conjugate:	No
Host:	Mouse
Species reactivity:	human, mouse, rat
Immunogen:	Recombinant protein of Human MITF
MW:	59 kD
Format:	Purified