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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
M3753-01A-APC.200 | 200 µl | - | - |
3 - 19 business days* |
993.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
MIB is an E3 ubiquitin ligase protein that mediates ubiquitination of Delta receptors, which act... more
Product information "Anti-Mib1, CT (E3 Ubiquitin-protein Ligase MIB1, Mind Bomb Homolog 1, DAPK-interacting Protein 1, DI"
MIB is an E3 ubiquitin ligase protein that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. It positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. It probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis. Applications: Suitable for use in FLISA and Immunohistochemistry. Other applications not tested. Recommended Dilution: FLISA: 1:1,000, Immunohistochemistry: 1:50-1:100, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Do not freeze APC conjugates. Light sensitive. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap., , Note: Applications are based on unconjugated antibody.
Keywords: | Anti-MIB1, Anti-DIP1, Anti-DIP-1, EC=6.3.2.-, Anti-Mind bomb homolog 1, Anti-DAPK-interacting protein 1, Anti-E3 ubiquitin-protein ligase MIB1, Anti-Zinc finger ZZ type with ankyrin repeat domain protein 2 |
Supplier: | United States Biological |
Supplier-Nr: | M3753-01A-APC |
Properties
Application: | FLISA, IHC |
Antibody Type: | Polyclonal |
Conjugate: | APC |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Synthetic peptide selected from the C-terminal region of human MIB (KLH). |
Format: | Affinity Purified |
Database Information
KEGG ID : | K10645 | Matching products |
UniProt ID : | Q86YT6 | Matching products |
Gene ID : | GeneID 57534 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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