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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-F48612-0.08ML | 80 µl | - | - |
3 - 10 business days* |
326.00€
|
||
NSJ-F48612-0.4ML | 400 µl | - | - |
3 - 10 business days* |
702.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
In 1X PBS, pH 7.4, with 0.09% sodium azide. Histone proteins H3, H4, H2A, and H2B function as... more
Product information "Anti-methyl-Histone H4 (Methyl-Lys20 specific)"
In 1X PBS, pH 7.4, with 0.09% sodium azide. Histone proteins H3, H4, H2A, and H2B function as building blocks to package eukaryotic DNA into repeating nucleosome units that are folded in higher order chromatin fibers. The nucleosome is composed of an octamer containing a H3/H4 tetramer and two H2A/H2B dimers, surrounded by approximately 146 base pairs of DNA. A diverse and elaborate array of post-translational modifications including acetylation, phosphorylation, methylation, ubiquitination, and ADP-ribosylation occurs on the N-terminal tail domains of histones. Protein function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [The UniProt Consortium]
Keywords: | Anti-HIST4H4, Anti-HIST1H4B, Anti-HIST1H4L, Anti-HIST1H4F, Anti-HIST1H4C, Anti-HIST1H4E, Anti-HIST1H4K, Anti-HIST1H4D, Anti-HIST1H4I, Anti-HIST1H4J, Anti-HIST2H4A, Anti-HIST2H4B, Anti-HIST1H4A, Anti-HIST1H4H, Anti-Histone H4, Histone H4 Antibody (Methyl-L |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | F48612 |
Properties
Application: | IHC, FC, WB, Dot Blot, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Amino acids surrounding the K20 methylation site of the human protein were used as the immunogen for this Histone H4 antibody. |
Format: | Purified |
Database Information
KEGG ID : | K11254 | Matching products |
UniProt ID : | P62805 | Matching products |
Gene ID | GeneID 121504 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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