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![Anti-MCM2 (Minichromosome maintenance complex component 2, BM28, CCNL1, cdc19, CDCL1, D3S3194, DNA r](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
M2749-30Z.100 | 100 µg | - | - |
3 - 19 business days* |
947.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
MCM2 (Minichromosome maintenance protein 2, also BM28) is a member of the MCM family of proteins.... more
Product information "Anti-MCM2 (Minichromosome maintenance complex component 2, BM28, CCNL1, cdc19, CDCL1, D3S3194, DNA r"
MCM2 (Minichromosome maintenance protein 2, also BM28) is a member of the MCM family of proteins. Although its predicted MW is 102kD, it runs anomalously at 125kD in SDS-PAGE. MCM2 forms a large, 450-600kD prereplication complex with MCM3 through 7 plus HBO1, and associates with the ORC to initiate DNA synthesis. Human MCM2 is 904 amino acids (aa) in length (Accession # P49736). It contains one C4-type zinc finger region (aa329-355) and a P-loop NTPase region (aa485-659) and at least 12 Ser/Thr phosphorylation sites in the N-terminal one-third of the molecule. MCM2 has several potential isoforms. There is an alternate start site at Met10 with or without a 47 aa substitution for aa 109-157, a deletion of aa 31-126, a Gly substitution for aa 113-132 coupled with a 69 aa insertion after Lys476, and a seven aa substitution for aa1-137. Over aa143-296, human MCM2 shares 99% aa identity with mouse MCM2. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot:1ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute by adding sterile 40-50% glycerol, PBS, 0.02% sodium azide. Aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: | EC=3.6.4.12 |
Supplier: | United States Biological |
Supplier-Nr: | M2749-30Z |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Goat |
Species reactivity: | human |
Immunogen: | Recombinant corresponding to aa143-296 of human MCM2 (E. coli). |
Format: | Affinity Purified |
Database Information
KEGG ID : | K02540 | Matching products |
UniProt ID : | P49736 | Matching products |
Gene ID | GeneID 4171 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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