Anti-MAGEL2

Anti-MAGEL2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG44392.50 50 µg - -

6 - 14 business days*

551.00€
 
Protein function: Probably enhances ubiquitin ligase activity of RING-type zinc finger-containing... more
Product information "Anti-MAGEL2"
Protein function: Probably enhances ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases, possibly through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. Acts as a regulator of retrograde transport via its interaction with VPS35. Recruited to retromer-containing endosomes and promotes the formation of 'Lys-63'-linked polyubiquitin chains at 'Lys-220' of WASHC1 together with TRIM27, leading to promote endosomal F-actin assembly (PubMed:23452853). Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Significantly promotes the cytoplasmic accumulation of CLOCK. [The UniProt Consortium]
Keywords: Anti-NDNL1, Anti-MAGEL2, Anti-Protein nM15, Anti-Protein nM15, Anti-MAGE-like protein 2, Anti-MAGE-like protein 2, Anti-Necdin-like protein 1, Anti-Necdin-like protein 1
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG44392

Properties

Application: FC, IHC (paraffin), WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Human MAGEL2 recombinant protein (aa. sequence: Q578-A847)
MW: 133 kD
Format: Antigen Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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