Anti-Macrophage Inflammatory Protein-1beta (MIP-1b)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
209-401-B97	100 µg		-	-	6 - 10 business days*		719.00€

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Protein function: Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of... more

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Product information "Anti-Macrophage Inflammatory Protein-1beta (MIP-1b)"

Protein function: Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8 T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5- mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B. [The UniProt Consortium]

Keywords:	Anti-LAG1, Anti-CCL4
Supplier:	Rockland Immunochemicals
Supplier-Nr:	209-401-B97

Properties

Application:	ELISA, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	full length recombinant human MIP-1beta protein
Format:	Purified