Anti-LSD1 (aa 100-150)

LSD1 is a flavin-containing nuclear protein having a N-terminal SWIRM domain, a C-terminal FAD-binding motif, and an amine oxidase domain. It functions as a transcriptional corepressor and catalyzes the flavin-dependent demethylation of Lys4 of histone 3 resulting in the formation of methyl-free lysine and release of formaldehyde. LSD1 has been found to be typically associated with CoREST and histone deacetylases 1 and 4 and participates in the silencing of endogenous neuron-specific genes.Synonyms: Amine Oxidase (flavin containing) Domain 2. Immunogen: peptide corresponding to a portion of human LSD1 amino acids 100-150. Formulation: (Request formulation change), 100 µg of peptide affinity-purified IgG in 200 µl PBS containing 0.2% gelatin and 0.05% sodium azide. Host: Rabbit. Applications: WB. Origin: Animal/Rabbit.