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This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene. Protein function: May act as receptor for class I MHC antigens. [The UniProt Consortium]
Keywords:
Anti-LIR8, Anti-LIR-8, Anti-CD85c, Anti-LILRB5, Anti-CD85 antigen-like family member C, Anti-Leukocyte immunoglobulin-like receptor 8, Anti-Leukocyte immunoglobulin-like receptor subfamily B member 5, LILRB5 Polyclonal Antibody
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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