Anti-LILRB2

Anti-LILRB2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-CAB10135.20 20 µl -

9 - 20 business days*

149.00€
 
Protein function: Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B,... more
Product information "Anti-LILRB2"
Protein function: Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles (PubMed:11169396, PubMed:12853576, PubMed:16455647, PubMed:20448110, PubMed:27859042). Involved in the down-regulation of the immune response and the development of tolerance. Recognizes HLA-G in complex with B2M/beta-2 microglobulin and a nonamer self-peptide (peptide-bound HLA-G-B2M) triggering differentiation of type 1 regulatory T cells and myeloid-derived suppressor cells, both of which actively maintain maternal-fetal tolerance (PubMed:20448110, PubMed:27859042, PubMed:16455647). Competes with CD8A for binding to class I MHC antigens. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions (PubMed:11875462, PubMed:12853576, PubMed:9548455, PubMed:9842885). [The UniProt Consortium]
Keywords: Anti-ILT-4, Anti-CD85d, Anti-LIR-2, Anti-MIR-10, Anti-Immunoglobulin-like transcript 4, Anti-CD85 antigen-like family member D, Anti-Leukocyte immunoglobulin-like receptor 2, Anti-Monocyte/macrophage immunoglobulin-like receptor 10
Supplier: Assay Genie
Supplier-Nr: CAB10135

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat

Database Information

UniProt ID : Q8N423 | Matching products
Gene ID GeneID 10288 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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