Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-V3146-20UG | 20 µg | - | - |
3 - 10 business days* |
332.00€
|
||
NSJ-V3146-100UG | 100 µg | - | - |
3 - 10 business days* |
752.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. The Lewis histo-blood group system... more
Product information "Anti-Lewis b, clone 2-25LE or LWB01"
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Lewis blood group antigens are carbohydrate moieties structurally integrated in mucous secretions. Lewis antigen system alterations have been described in gastric carcinoma and associated lesions. Anomalous expression of Lewis B antigen has been found in some non-secretory gastric carcinomas and colorectal cancers. Protein function: May catalyze alpha-1,3 and alpha-1,4 glycosidic linkages involved in the expression of Vim-2, Lewis A, Lewis B, sialyl Lewis X and Lewis X/SSEA-1 antigens. May be involved in blood group Lewis determination, Lewis-positive (Le(+)) individuals have an active enzyme while Lewis-negative (Le(-)) individuals have an inactive enzyme. Also acts on the corresponding 1,4-galactosyl derivative, forming 1,3-L-fucosyl links. [The UniProt Consortium]
Keywords: | Anti-FT3B, Anti-FUT3, Anti-Lewis FT, Anti-FucT-III, EC=2.4.1.65, Anti-Fucosyltransferase 3, Anti-Fucosyltransferase III, Anti-Galactoside 3(4)-L-fucosyltransferase, Anti-Blood group Lewis alpha-4-fucosyltransferase, Lewis b Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | V3146 |
Properties
Application: | IF, IHC |
Antibody Type: | Monoclonal |
Clone: | 2-25LE / LWB01 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human, guinea swine |
Immunogen: | Mucin isolated from human ovarian cyst fluid was used as the immunogen for this Lewis b antibody. |
Format: | Purified |
Database Information
KEGG ID : | K00716 | Matching products |
UniProt ID : | P21217 | Matching products |
Gene ID : | GeneID 2525 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
more
You will get a certificate here
Viewed