Anti-LEF1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA002087.25	25 µl		-		7 - 10 business days*		320.00€
ATA-HPA002087.100	100 µl		-		7 - 10 business days*		450.00€

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Protein function: Transcription factor that binds DNA in a sequence-specific manner... more

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Product information "Anti-LEF1"

Protein function: Transcription factor that binds DNA in a sequence-specific manner (PubMed:2010090). Participates in the Wnt signaling pathway. Activates transcription of target genes in the presence of CTNNB1 and EP300. PIAG antagonizes both Wnt-dependent and Wnt-independent activation by LEF1. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by LEF1 and CTNNB1 (PubMed:11266540). Regulates T-cell receptor alpha enhancer function (PubMed:19653274). Required for IL17A expressing gamma-delta T-cell maturation and development, via binding to regulator loci of BLK to modulate expression. May play a role in hair cell differentiation and follicle morphogenesis. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 98% and to rat: 96%

Keywords:	Anti-LEF1, Anti-LEF-1, Anti-TCF1-alpha, Anti-Lymphoid enhancer-binding factor 1, Anti-T cell-specific transcription factor 1-alpha
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA002087

Properties

Application:	ChIP, ICC, WB, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: SDVNSKQGMS RHPPAPDIPT FYPLSPGGVG QITPPLGWQG QPVYPITGGF RQPYPSSLSV DTSMSRFSHH MIPGPPGPHT TGIPHPAIVT PQVKQEHPHT DSDLMHVKPQ HEQRKEQEPK RPHIKKPLNA FMLY (ATA-APrEST84768)