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![Anti-LAG-3 (Lymphocyte Activation Gene-3, FDC Protein, CD223) (APC)](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
L1050-61P.100 | 100 tests | - | - |
3 - 19 business days* |
916.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
LAG-3, also known as CD223, is a type I membrane protein that belongs to the immunoglobulin... more
Product information "Anti-LAG-3 (Lymphocyte Activation Gene-3, FDC Protein, CD223) (APC)"
LAG-3, also known as CD223, is a type I membrane protein that belongs to the immunoglobulin superfamily (IGSF). The extracellular domain of LAG-3 contains a V-set and three C2-set Ig domains. LAG-3 is expressed on activated T cells, NK cells and B cells. It binds to MHC class II molecules with much higher avidity than CD4, a LAG-3 structural homolog. Mouse and human LAG-3 have been shown to be negative regulators of T cell function and homeostasis. The extracellular domain of human and mouse LAG-3 share 69% aa sequence identity. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilutions: Flow Cytometry: 10ul labels 1x10e6 human peripheral blood mononuclear cells (PBMCs) treated with PHA, Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Supplier: | United States Biological |
Supplier-Nr: | L1050-61P |
Properties
Application: | FC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Goat |
Species reactivity: | human |
Format: | Affinity Purified |
Database Information
UniProt ID : | P18627 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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