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![Anti-Kv1.8](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES20686.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES20686.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Potassium channels represent the most complex class of voltage-gated ion channels from both... more
Product information "Anti-Kv1.8"
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It is specifically regulated by cGMP and postulated to mediate the effects of substances that increase intracellular cGMP. This gene is intronless, and the gene is clustered with genes KCNA Protein function: Mediates voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. The channel activity is up-regulated by cAMP. [The UniProt Consortium] Recommended dilutions: WB 1:1000-2000, IHC 1:100-200. Cellular localization: Membrane , Multi-pass membrane protein .
Keywords: | Anti-KCNA10, Anti-Voltage-gated potassium channel subunit Kv1.8, Anti-Potassium voltage-gated channel subfamily A member 10, Kv1.8 rabbit pAb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES20686 |
Properties
Application: | WB, IHC, IF |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, rat, mouse |
Immunogen: | Synthetic Peptide of Kv1.8 AA range: 194-244 |
MW: | 58 kD |
Format: | Purified |
Database Information
KEGG ID : | K04881 | Matching products |
UniProt ID : | Q16322 | Matching products |
Gene ID | GeneID 3744 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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